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Description

Locus has begun dosing participants in the phase II portion of the trial, which focuses on a combination of IV and urethral delivery of the CRISPR-based treatment plus oral antibiotics

10.1038/nature10337 9 DescheneE

The compound appears at measurable concentrations in human plasma, saliva, and urine, and its levels are known to decline with age a pattern that has driven considerable interest in its study as a research tool